Make sure Titanium is up to date. This is done by Alesia Lowe-Jenkins. Help > Check for updates.
Add the eRx site to the Trusted Sites list via Internet Options (can be accessed via the 'gear' icon in Internet Explorer - eRx in Titanium uses an embedded IE browser window). The URL is
I am thinking that there must be an issue with the installed version of ScriptX. I've reuploaded a new copy of the ScriptX installer at the URL below. Please download this and execute the installer again on the PC that is receiving the popup. When (or if) it gives you the option to 'Repair' or 'Remove', click on 'Remove'. Once the removal is complete, execute the installer once again and run through the install process.